Kane has been out of action since April 9, when he damaged his ankle against Manchester City, in the Champions League quarter-final.
The England captain says he is ready to return to the side, as Spurs prepare to take on Liverpool in the biggest match in the club’s history.
Pochettino has to decide whether to keep faith with the players who completed the remarkable semi-final comeback against Ajax, led by hat-trick hero Lucas Moura, or gamble on Kane.
“All the decisions are tough decisions, it is so painful.
“But it is part of my job to decide how to pick the starting XI. This is not going to be easy to make a decision tomorrow.
“We are going to take the best decision to try and win, but like always in football, it is so painful when this type of game arrives and you can only use from the beginning eleven players.
“That is the most painful situation,” Pochettino told a press conference on Friday.
