The players are Mohamed Elneny, Rob Holding and Granit Xhaka.
Arsenal disclosed this in a statement via their website on Thursday.
The Gunners head to the game following a 1-0 victory against Norwich City in their last Premier League encounter.
The statement read, “Mohamed Elneny – Left hamstring. Mo has worked hard with the medical team after suffering a hamstring strain and is aiming to be back in full training next week.
“Rob Holding – Right knee. Rob sustained heavy bruising to his right knee during training ahead of the Norwich City match last weekend. Rob has progressed his rehabilitation back into training but will not be available for Saturday’s match.
“Granit Xhaka – Suspended. Further to receiving a red card against Manchester City, Granit is serving the second match of a three-match suspension.”
