Egyptian authorities said other vessels were moving again after the gigantic Ever Given container ship was refloated, which was seen by witnesses for the Reuters news agency.
The Ever Given has started heading towards the Bitter Lakes area, according to Egyptian television.
“She’s free,” said an official involved in the salvage operation.
Efforts to get the ship moving again appeared to have been frustrated after high winds swung it back across the channel after its partial refloating earlier on Monday.
There had been intensive efforts to push and pull it with 10 tug boats and vacuum up sand with several dredgers at high tide.
Osama Rabei, the head of the Suez Canal Authority, confirmed the ship had responded successfully to “pull-and-push manoeuvres”.
Speaking earlier, he said workers had almost completely straightened the vessel’s course and that the stern had moved 102 metres (334 feet) from the canal bank.
He said it could take from two-and-a-half to three days to clear the backlog.
The oil price fell as news of developments in the canal emerged, with the price of Brent crude down by 2% to just over $63 (£46) a barrel.
It had been feared the Panama-flagged, Japanese-owned ship might be stuck for weeks.
Dredgers overnight shifted more than 27,000 cubic metres of sand – to a depth of 18m (59ft) – with work taking place around the clock.
The skyscraper-sized Ever Given became stuck in Egypt’s Suez Canal last Tuesday and the resulting disruption to the vital waterway has held up £6.5bn in global trade each day.
More than two dozen vessels opted for the alternative route between Asia and Europe around the Cape of Good Hope, adding around a fortnight to journeys and threatening delivery delays.
The 400m (1,312ft) long Ever Given became jammed diagonally across a southern section of the canal in high winds.
As of Saturday, 321 boats were waiting to get through the canal, including dozens of container ships, bulk carriers and liquefied natural gas (LNG) or liquefied petroleum gas (LPG) vessels.
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