Los Blancos go into the game knowing that victory will extend their lead over Barcelona at the top of the table to seven points.
They will have to do that without their most expensive buy, Eden Hazard, who picked up a knock against Espanyol and missed the win over Getafe.
Zidane will, however, have other attackers like Karim Benzema, Vinicius Junior and Gareth Bale available for selection.
Kick-off is 1pm West African time.
Real Madrid squad to face Athletic include; Goalkeepers: Courtois, Areola, Altube.
Defenders: Carvajal, Militao, Ramos, Marcelo, Mendy, Javi Hernández.
Midfielders: Kroos, Modric, Casemiro, Valverde, Isco.
Forwards: Benzema, Bale, Lucas Vázquez, Jovic, Asensio, Brahim, Mariano, Vinicius, Rodrygo.
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